A laser power control system and related method for reducing a settling time in a target laser power transition are disclosed. The laser power control system includes a state decision circuit, for generating a state decision signal according to a selected operational state of a target circuit; a plurality of buffers, for storing a plurality of control data corresponding to a plurality of candidate operational states of the target circuit respectively; and a multiplexer, coupled between the state decision circuit and the buffers, for coupling a selected buffer of the buffers and the target circuit according to the state decision signal for outputting a control datum stored in the selected buffer to the target circuit.