There are disclosed systems, computer program products, and methods for self-tuning memory. In an embodiment, a method for self-tuning memory comprises setting a tuning interval and a target range for free memory for a memory pool. If memory consumption falls outside of the set target range for free memory during a tuning interval, a new target size for the memory pool is set based on the target range for free memory. Memory allocation for the memory pool is increased or decreased for the next tuning interval, such that the new target size for the memory pool is reached. A decrement rate may be used to provide a controlled decrease of the memory pool over a plurality of tuning intervals if necessary, until the new target size for the memory pool is reached.