A medical item inventory system includes a plurality of different types of stored medical items. The system includes medical item dispenser devices which can be selectively operated to dispense requested medical items to authorized users. The system can monitor the medical item inventory to automatically determine a low supply of a particular medical item type. In response to a determination of a low supply of a particular medical item type, the system automatically electronically places a purchase order to a supplier of the particular medical item type. The purchase order includes the particular medical item type, a requested quantity, and a requested delivery date. The requested quantity and delivery date can both be calculated by the system based on a rate of use of the particular medical item type.