Disclosed is a wireless communication system which carries out spatial multiplexing communication forming multiple spatial channels between a pair of a transmitter with multiple antennas and a receiver with multiple antennas, having the transmitter and the receiver. In the system, the multiple spatial channels are divided into one or more groups, the transmitter transmits reference signals corresponding to spatial channels in succession in a time-division manner for each group, and the receiver acquires a channel matrix whose column vectors are transfer functions of the spatial channels obtained from the reference signals for each group and spatially demultiplexes a receive signal using a receive weight obtained based on the channel matrix.