The present invention relates to a chemical genus of biaryl nitrogen-attached heterocycles that are inhibitors of LTA4H (leukotriene A4 hydrolase). The compounds have the general formula: ##STR00001## They are useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders.

 
Web www.patentalert.com

< Therapeutic .beta.-lactams

> Anti-inflammatory and analgesic heterocyclic amidines that inhibit nitrogen oxide (NO) production

> Aryl, aryloxy, alkyloxy substituted 1H-indol-3-yl glyoxylic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
~ 00589