The invention relates to a drive unit for motor vehicles, comprising an internal combustion engine, a transmission which is mounted downstream therefrom and is provided with an integrated differential, and a separating clutch that is disposed between the internal combustion engine and the transmission. The differential is driven via a bevel wheel and a bevel-gear drive comprising a drive pinion on an output shaft of the transmission. In order to create a drive unit that is advantageous regarding structure and efficiency, the bevel wheel (48) of the differential (16) is placed laterally from the separating clutch (26) from a vertical perspective and partly protrudes (A) therefrom in an axial direction.