Embodiments of the invention provide systems and methods for water purification. The systems have a preheater, a degasser, an evaporation chamber, a demister, and a control system, wherein the control system permits operation of the purification system through repeated cycles without requiring user intervention or cleaning. The system is capable of removing, from a contaminated water sample, a plurality of contaminant types including: microbiological contaminants, radiological contaminants, metals, salts, volatile organics, and non-volatile organics.