According to an aspect of the present invention, medical devices are
provided which include a metallic substrate and a polymeric region
disposed over and in contact with the metallic substrate. The polymeric
region includes (a) a fluorine-containing polymer that contains at least
one type of fluorine-containing monomer selected from a vinylidene
fluoride monomer, a hexafluoropropylene monomer, and a combination
thereof, and (b) an adhesion promoting copolymer that contains (i) at
least one type of first monomer that covalently or non-covalently bonds
with the metallic substrate and (ii) at least one type of second monomer
selected from acrylate monomers, methacrylate monomers,
fluorine-containing monomers, and combinations thereof.