In a method and system for data and signal transfer between different sub-units of a medically-related system, in particular a CT system, digitized signals and digital data are transmitted together on a transmission line by means of serial multiplexing. The digitized signals and the digital data are transferred combined into individual packets having a length that is so small that the adherence to a predetermined updating rate of the signals is achieved. The expenditure for the wiring as well as for future expansions in medically-related systems can be significantly reduced.