A procedure for squeezing off and sealing a tube, in which the tube is positioned between a sonotrode and an associated anvil, counter electrode, of an ultrasonic device, and the sonotrode is activated and displaced relative to the counter electrode for squeezing off and sealing the tube. In order to enable automatic squeezing off and sealing of a tube without individually entering the data of the tube into an ultrasonic welding device in advance, the invention proposes positioning the tube and fixing it between the sonotrode and the counter electrode, retrieving stored welding parameters on the basis of the characteristic variable and activating the sonotrode and moving the sonotrode and counter electrode in relation towards each other for consolidating and sealing the tube.