The present invention relates generally to methods and related
compositions using flavonoids and/or indanes extracted from the stems and
leaves of C. quadrangularis to reduce weight and inhibit lipase,
.alpha.-amylase and .alpha.-glucosidase activity in mammals. By example
and not by way of limitation, embodiments of the present disclosure, a
composition and related methods for reducing body weight and/or
inhibiting any combination of lipase, .alpha.-amylase and
.alpha.-glucosidase is provided. The composition contains an effective
amount of one or more flavonoids or indanes selected from
3-O-rhamnopyranosylkaempferol,
3-(4-hydroxybenzylidene)-2-(2,5-dihydroxyphenyl)-1-(4-hydroxyphenyl)indan-
e-4,6-diol, quercitrin, rhamnitrin, rhamnocitrin, quercitrin-3-O''-acetate
and parthenocissin A.