In a wireless communication system, a method and apparatus for reference signal selection is disclosed. In accordance with the preferred embodiment of the present invention, a first reference signal in a first cell is pseudo-randomly selected from a predetermined limited set of reference signals for transmission on a first channel resource. A second reference signal in the cell is pseudo-randomly selected from the predetermined limited set of reference signals for transmission on a second channel resource, where the predetermined limited set of reference signals is common among the first cell and at least a second cell.