Disclosed are systems and methods for use in filtering electronic messages using business heuristics. In one aspect, a method includes determining whether the electronic message is associated with a desirable business, and adjusting the likelihood of delivering the electronic message to an intended recipient of the message if the electronic message is determined to be associated with the desirable business. In a more specific embodiment, the method further includes assigning a spam-score to the electronic message based on a likelihood that the electronic message is not unwanted by the intended recipient, blocking delivery of the electronic message to the intended recipient when the spam-score does not cross an overall threshold, and delivering the electronic message to the intended recipient based on the adjusted likelihood when the electronic message is determined to be associated with the desirable business.