A syringe barrel for pre-filled syringe formulation capable of suppressing the adhesion of air bubbles, and a pre-filled syringe formulation having the adhesion of air bubbles suppressed, are provided, and a process allowing efficient production of the syringe barrel is provided. A syringe barrel for pre-filled syringe formulation having the interior surface treated by corona discharge; a pre-filled syringe formulation having a drug solution filled and sealed in the syringe barrel; and a process for producing a syringe barrel for pre-filled syringe formulation, including subjecting the interior surface of a syringe barrel to a corona discharge treatment.