A grooved electrode adapted for interfacing cellular matter is provided. The grooved electrode includes grooves adapted for electrically interfacing the grooved electrode with cellular matter growing along the body of the grooved electrode. Further, the grooved electrode includes a wireless transponder adapted to electrically interface with cellular matter and to relay such interactions via RF signals. The RF signals received by the wireless transponder are modulated in response to electrical signals generated by the cellular matter, which are detected by the transponder. The grooved electrode may be implanted within peripheral nerves for treating various neurological conditions, which may include nerve rehabilitation and prosthetic actuation, severe pain, obstructive sleep apnea and so forth.