A routing/hub device and a data management system are provided to managing test and monitoring devices such as portable test and monitoring devices in healthcare. The routing/hub device interfaces through a variety of communication means with one or more peripheral devices collecting data and configuring those devices based on user input or input from the data management system. Collected data is provided to the data management system for actions such as analysis, reporting, and the like. Alerts and messages may also be provided to designated recipients directly or through the data management system based on predefined rules for collected data.