A compound of the formula (I): ##STR00001## a pharmaceutically acceptable salt or solvate thereof,wherein Ring Q is optionally substituted monocyclic aryl, optionally substituted monocyclic heteroaryl, optionally substituted fused aryl or optionally substituted fused heteroaryl, Y.sup.1 is a bond or --NR.sup.6-- or the like, Ring A is optionally substituted nonaromatic heterocyclediyl, a group of the formula: -Y.sup.2Z.sup.1- is a group of the formula: ##STR00002## R.sup.7 are each independently hydrogen, optionally substituted lower alkyl or the like, R.sup.8 and R.sup.9 are each independently hydrogen or optionally substituted lower alkyl, n is an integer between 1 and 3, Z.sup.1 is a bond, --O--, --S-- or --NR.sup.9--, Ring B is optionally substituted aromatic carbocyclediyl or optionally substituted aromatic heterocyclediyl, Y.sup.3 is a bond, optionally substituted lower alkylene optionally intervened by --O--, optionally substituted lower alkenylene or the like, and Z.sup.2 is COOR.sup.3 or the like.

 
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