The invention provides methods and compositions for diagnosing risk of low BMD and risk of osteoporosis based on the detection of SNP identity for human chromosome 1p36 polymorphisms designated in the NCBI SNP database (dbSNP) as rs2794328, rs446529, rs397559 and rs1802353.

 
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> Method to determine single nucleotide polymorphisms and mutations in nucleic acid sequence

> CHR and POMC effects on animal growth

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