A fluid line coupling is disclosed for connection with hollow tubing. The coupling includes a body portion having a passageway for fluid communication with the tubing. A first wall extends from the body portion radially surrounding the passageway, and a second wall radially surrounds the first wall forming a pocket between the walls. The second wall includes an aperture for fluid communication with the pocket. An open ended aperture may be included in a radial array of apertures. The first wall may include a tapered surface for securing the tubing. A third wall may radially surround the second wall forming a well for an adhesive for filling the aperture and pocket. A second set of walls may extend in an axially opposite direction from the first set. The coupling may be included in a connection assembly with hollow tubing comprising a PVC material providing fluid communication with a medical instrument.