Frequency-dependent cancellation separates a plurality of interfering signals received by a plurality of receivers. Received wideband single-carrier signals or multicarrier signals are separated into a plurality of narrowband subcarriers. Sub-carrier frequencies and frequency-band characteristics may be selected with respect to channel characteristics (e.g., coherence bandwidth, interference, etc.). A cancellation circuit provides complex weights to the sub-carrier components. Weighted components associated with each sub-carrier frequency are combined to separate a plurality of interfering signals. Optionally, a plurality of the separated subcarriers may be combined to reconstruct at least one transmitted single-carrier signal from a plurality of frequency components. Combining may include decoding, such as to reconstruct a coded sequence of data symbols transmitted via direct-sequence coding, code division multiple access (CDMA), multicarrier CDMA, carrier interferometry (CI), CI coding, or coded orthogonal frequency division multiplexing.