The invention pertains to novel cyclin dependent kinase inhibitors (cdks) and specifically, but not exclusively, as inhibitors of cdk/cyclin complexes. As described herein, the inhibitors of this invention are capable of inhibiting the cell-cycle machinery and consequently may be useful in modulating cell-cycle progression, ultimately controlling cell growth and differentiation. Such compounds would be useful for treating subjects having disorders associated with excessive cell proliferation.

 
Web www.patentalert.com

< Expression of cyclin G1 in tumors

> Immunoglobulin E vaccines and methods of use thereof

> Methods and compositions for inhibiting HIV infection

~ 00552