A nutritional formulation for the treatment of inflammatory conditions of the gastrointestinal tract (particularly Crohn's Disease in paediatric patients) comprises: (a) a lipid source, (b) a carbohydrate source, and (c) a protein source. wherein the lipid source comprises a weight ratio of n-6:n-3 fatty acids of 1:1 to 3:1, at least 90% by weight of the n-3 fatty acids in the lipid source are provided by .alpha.-linolenic acid and at least 90% by weight of the n-6 fatty acids in the lipid source are provided by linoleic acid and components (a), (b) and (c) together provide at least 400 kcal of energy per 100 g total weight of (a)-(c).