The present invention relates to methods of preventing, managing and/or treating blood sugar disorders, particularly those related to diabetes, by stimulating pancreas externally and non-invasively. Therapeutically repairing and regenerating beta cells of islets of langerhans enhance their ability to produce insulin to treat high blood sugar. The transformation of insensitive or impaired islets of langerhans results in an increased insulin secretion and in increased insulin level in blood plasma. This improves the glucose toxicity and improves beta cells dysfunction. This also regulates the pancreatic secretion that induces a feeling of satiety, which leads to weight loss.