Load balancer management is described herein. In one implementation a load balancer system includes servers for hosting content on a network site, disparate load balancers that manage the servers to substantially balance data communications across the servers, and a load balancer management service which includes an application program interface (API) that provides for universal communication with the different interfaces of the disparate load balancers. Each of the disparate load balancers may be controlled via a different interface. The API is configured to receive an instruction set to manage the disparate load balancers, and to communicate the instruction set as translated instruction sets to each of the disparate load balancers via the respective different interfaces. The load balancer management service can be implemented as a Web-based service.