A magazine tube and barrel clamp with integral target illuminator, wherein a laser module can be incorporated is provided for a firearm having a magazine tube and a barrel. The frame defines a clamping sleeve for substantially encircling the magazine tube and a barrel receiving channel for receiving a diameter of the barrel, wherein the magazine tube and the barrel are thus fixed in a predetermined spacing. The frame further defines an illuminator recess for receiving a substantial portion of a reflector in the target illuminator, thereby shielding the target illuminator from contact with external surfaces. A driver circuit is retained within the frame to selectively operate the target illuminator and a laser sight, wherein the target illuminator can be a solid-state light emitting device.