Inhibitors of the phosphatase activity of soluble epoxide hydrolase (sEH) are provided and are useful for in the treatment of diseases. These Inhibitors are based on derivatives of various epoxide hydrolase substrates that mimic the enzyme substrate so that there Is stable Interaction with the enzyme catalytic site. These inhibitors are potentially useful for the treatment of hypertension, vascular inflammation, renal inflammation, and lung disease.

 
Web www.patentalert.com

< Parakeratosis inhibitor, pore-shrinking agent,or rough skin preventing/ameliorating agent, and external composition for skin

> TOLL LIKE RECEPTOR (TLR) SIGNALING ANTAGONIST

> Heterologous Protein Production Using The Twin Arginine Translocation Pathway

~ 00540