The present invention relates to liquid chromatographic chiral stationary
phases (CSPs) and their preparation. The CSPs are based on
carbamate-derivatized polysaccharides that are covalently bound onto
inorganic oxide carriers via unique linkage chemistry. The present
invention also relates to methods of obtaining the said linkages, which
include derivatizing and functionalizing the polysaccharides, and also
chemically bonding the functionalized carbamate-derivatized
polysaccharides onto inorganic oxide carriers. The polysaccharide
derivatives so obtained can be used as materials for the liquid
chromatographic chiral separation of enantiomers. The preferred inorganic
oxides are silica, zirconium oxide, and aluminum oxide. Cellulose and
amylose are the preferred chiral polysaccharides.