Delayed release oral pharmaceutical formulations and methods for enhanced
intestinal drug absorption. The formulation comprises a first population
of carrier particles comprising a drug and a penetration enhancer which
are released at a first location in the intestine, and a second
population of carrier particles comprising a penetration enhancer and a
delayed release coating or matrix. This penetration enhancer is released
at a second location in the intestine downstream from the first location
and enhances absorption of the drug when it reaches the second location.