A mobile, real-time system for delivering an aerosol spray to a treatment area while maintaining the fluid within a closed environment for providing maximum personal protection to the operators handling the fluid during the transfer and application of the fluid. The invention includes a spraying device for producing a precise degree of liquid droplet generation on a repeatable basis by combining a specified rate of regulated flow of liquid material with a regulated flow of high-pressure air. The delivery system includes a closed loop system for calibrating a liquid pump, which regulates the flow of liquid within the system. A controller is coupled to the components of the delivery system for control thereof. The operator of the delivery system communicates with the controller through a user interface, which provides the operator with manual and automatic controls of the delivery system, such as the closed environment calibration of the pump and transfer of fluid from an external source to the delivery system.