The present invention concerns compounds of formula (I), and
pharmaceutically acceptable salts or solvates thereof, or solvates of
such salts, which compounds inhibit carboxypeptidase U and thus can be
used in the prevention and treatment of diseases where inhibition of
carboxypeptidase U is beneficial. In further aspects, the invention
relates to compounds of the invention for use in therapy; to processes
for preparation of such new compounds; to pharmaceutical compositions
containing at least one compound of the invention, or a pharmaceutically
acceptable salt or solvate thereof, as active ingredient; and to the use
of the active compounds in the manufacture of medicaments for the medical
use indicated above.