A portable computer that is ergonomic and solvent resistant is disclosed. The computer may have an exterior surface that is made from a soft polymer, so that it will shield a user from exposure to heat while providing a positive tactile feel and shielding the computer from impact. The computer may comprise a number of input output devices with distinct controls arranged about the body of the computer so that a user may comfortably operate each the devices with one hand. The housing of the computer may be sealed, so that it will be resistant to liquid and particulate infiltration, and may be easily wiped clean and disinfected.