System and method for automatically measuring the delay of tissue motion and deformation. For example, asynchrony may be measured between the left and right ventricles and within the left ventricle. A measurement feature may be defined by default or obtained using a user input. A reference time and a search interval are identified. The search interval may be based on the reference time, or input or modified by a user. A time delay of the measurement feature within the search interval is calculated for each sample. At least one color is assigned to the samples corresponding to the calculated time delay.