Methods for delivery of caffeine, compositions including caffeine, and methods of making such compositions are disclosed. Generally, the method of delivering caffeine includes topically administering to a mucosal skin surface of a subject a dose of caffeine effective to increase alertness in the subject. The compositions generally include a lip balm base and caffeine. The methods of making the compositions generally include melting a lip balm base, dissolving caffeine in a solvent, adding the dissolved caffeine to the molten lip balm base, and allowing the lip balm base/caffeine mixture to cool.