A low profile chassis and suspension system for a road vehicle. The chassis supports a payload section or cargo compartment, such as for a delivery truck, ambulance, or shuttle bus. The chassis includes a largely planar frame having a top surface which is located beneath the rotational axes of the rear wheels. The wheel suspension system is particularly compact and close to the road surface. A trailing arm-type wheel support supports a stub axle in a cantilevered fashion. A spring urges the wheel support apart from the frame. A planar portion of the wheel support, the wheel support pivot joints, and the spring are located beneath the rotational axis of the wheel. In another embodiment, the frame includes a recessed pocket which facilitates use of ramp for wheel chair access.