An in-vivo imaging device including a ballast that may for example orient
such device in a known orientation relative to the gravitational force on
such ballast. Such imaging device may, for example, assume a known
orientation when it is free to move, and may capture images from such
known orientation. The device may include one or more imagers, which may
be oriented at different angles or points of view (e.g., forward and
transverse). A method of use may include moving a patient so that the
device inside the patient images different fields of view.