The invention refers to a method for production of
1(10).beta.-epoxy-13-dimethylamino-5,7a,6,
11.beta.(H)-guaia-3(4)-en-6,12-olide hydrochloride, the lyophilized,
antitumor preparation having radio-sensitizing and immunomodulating
activities, including extraction of the natural raw material endemic
plant Artemisia glabella Kar. et Kir., separation obtained resin on
individual components with receiving technical arglabin from which
dimethylaminoarglabin hydrochloride is synthesized, with its subsequent
purification, drying and lyophilization. In this method the extraction is
carried out with use of fluid carbon dioxide as extragent at pressure
150.+-.2-10.sup.5 Pa and temperature 60.degree. C. i 0.5, the separation
resin on individual components is carried out by method of preparative
fluid chromatography with application of reversed phase C.sub.18, at the
synthesis of dimethylaminoarglabin hydrochloride technical arglabin is
solved in acetonitrile at the weight ratio 1:10 with addition
dimethylammonium dimethylcarbamat in the molar ratio 1:1.62.