Provided are compounds of formula I that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes meilitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase. ##STR00001##

 
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< Imidazolo-, oxazolo-, and thiazolopyrimidine modulators of TRPV1

> Substituted imidazole compound and use thereof

> Selective androgen receptor modulators, analogs and derivatives thereof and uses thereof

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