The invention provides a method for treating an autoimmune disease in a
subject by administering an interferon antagonist and a Flt3 ligand
(Flt3L) antagonist. The invention also provides compositions containing
one or more interferon antagonists, and one or more Flt3L antagonists, an
in vitro assay for determining a subject's risk for developing an
autoimmune disease, and kits for use, inter alia, with the assay.