A medical article comprising: (a) a therapeutic agent; and (b) a release
region comprising (i) a polymer and (ii) a filler comprising inorganic
platelet particles. Upon placement of such a medical article at a
position on or within a patient, the release region regulates the rate of
release of the therapeutic agent from the medical article to the patient.
An example of a filler is one comprising inorganic platelet particles.
Examples of medical articles include, for instance, drug delivery
patches, and implantable or insertable medical devices. Also described
are methods of releasing a therapeutic agent to a patient using such
medical articles, and methods of making such medical articles.