A wireless peripheral interface is used for coupling with a Universal Serial Bus (USB) port for connecting a wireless peripheral with a host computer or controller. Wireless peripheral devices (e.g., keyboard, mouse, trackball, touch pad, joysticks, and game controllers) transmit communication signals, e.g., radio frequency (RF) signals, to the peripheral interface, which are received and processed into formats suitable for transmission to the host computer or controller via USB, either alone or in combination with other standard external bus systems, such as serial and PS/2.