The present application describes sulfonylaminovalerolactams and derivatives thereof of Formula I: ##STR00001## or pharmaceutically acceptable salt forms thereof, wherein ring G is a mono- or bicyclic carbocycle or heterocycle. Compounds of the present invention are useful as inhibitors of trypsin-like serine proteases, specifically factor Xa.

 
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> Substituted pyrroline kinase inhibitors

> Ligand to GPR8

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