A removable protective covering is provided that can be secured about an external fixation device on the upper or lower extremity of a patient. The covering includes a fabric form that is sized and configured to accommodate varying sizes of external fixation devices and uses readily engageable/releasable closure elements or fasteners to securely engage the covering about the fixator and the extremity. A drawstring closure may be provided at the open ends of the covering to tighten the end about the patient's limb. Ventilation features may be provided including vents with and without additional devices to generate air flow through the covering. The covering for a lower extremity fixation device may be configured for removably attachment to a foot plate and the foot plate itself may be configured to support or attach to the fixation device.