The present invention provides 2-furancarboxylic acid hydrazide compounds represented by General Formula (I) below, and prodrugs, physiologically acceptable salts, hydrates, solvates thereof: ##STR00001## wherein A is a group represented by Formula (a) or the like: ##STR00002## (wherein either R.sup.4 or R.sup.5 represents cyano, nitro or the like, and the other represents a hydrogen atom or the like); either R.sup.1 or R.sup.2 represents a group: -D-(X)m-R.sup.6 or the like, and the other represents a group: -E-(Y)n-R.sup.7, hydrogen atom, aryl or the like; R.sup.3 is a hydrogen atom or the like; D and E independently represent aryl; X and Y independently represent O or the like; R.sup.6 and R.sup.7 independently represent alkyl, aryl, arylalkyl or the like; and m and n are independently 0 or 1, provided that the aryl is optionally substituted.