Patient input indicating the occurrence of an event and information relating to the event may be collected by a computing device. In some examples, the patient input is received via an event indication input mechanism of a medical device programmer. A clinician may review the event information to evaluate the efficacy of a therapy system (e.g., a particular therapy program or program group) or a patient's condition. In one example, a patient may activate an event indication input mechanism to indicate the occurrence of a seizure symptom, and input information relating to the seizure, such as the duration, severity, type of seizure or efficacy of a therapy system implemented to manage seizures.