Disclosed are compounds of formula (I) ##STR00001## Where Ar.sub.1, X, R.sub.3, R.sub.4, R.sub.5 and R.sub.6 are defined herein. The compounds of the invention inhibit production of cytokines and are thus useful for treating cytokine mediated diseases. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.

 
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< N-[[4-fluoro-2-(5-methy-1H-1,2,4-triazol-1-yl)phenyl]methyl]-4-,6,7,9-tetr- ahydro-3-hydroxy-9,9-dimethyl-4-oxo-pyrimido[2,1-c][1,4]oxazine-2-carboxam- ide as an HIV integrase inhibitor

> Mercaptoimidazoles as CCR2 receptor antagonists

> Chemical compounds

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