A thrombectomy apparatus for breaking up thrombus or other obstructive material in a lumen of a vascular graft or vessel includes a flexible sheath and a wire positioned within the flexible sheath, wherein the wire and flexible sheath are relatively movable. The wire is substantially sinuous in configuration and assumes a substantially sinuous shape when deployed from the flexible sheath and a straighter configuration when retracted into the flexible sheath. The wire is operatively connected to a motor for rotation of the wire to enable the deployed wire to break up the thrombus or other obstructive material.