The invention is a silicon substituted oxyapatite compound (Si--OAp) for use as a synthetic bone biomaterial either used alone or in biomaterial compositions. The silicon substituted oxyapatite compound has the formula Ca.sub.5(PO.sub.4).sub.3-x(SiO.sub.4).sub.xO.sub.(1-x)/2, where 0

 
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> Anti-CD26 monoclonal antibodies as therapy for diseases associated with cells expressing CD26

> Solid oral dosage form containing an enhancer

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