Apparatus and methods for separating different polynucleotide populations in a mixture are provided, wherein different polynucleotides or polynucleotide populations are captured on different solid support. After hybridization, polynucleotides are selectively released from a selected support by altering a physical property of that support. The released polynucleotides can be eluted from a common flow path and isolated.

 
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< Factor VII or VIIA-like molecules

> Compositions and methods for inhibiting the synthesis or expression of MMP-1

> Inhibition of gastric acid production and/or secretion

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