For an improved method for examining the skin of a proband, in particular as part of a skin cancer screening examination or a skin cancer therapy, it is provided that an epiluminescence microscopy image (B) is first taken of a distinctive skin site and by analysis of the image (B) the skin site is rated as suspect or inconsequential with regard to the presence of a disease. In a further method step it is provided that an image (B') of a skin site rated as suspect is recorded by means of optical coherence tomography and the diagnosis of disease is verified or refuted on the basis of this image (B'). A device particularly suited to the performance of the method comprises an epiluminescence microscopy device (2) and an optical coherence tomography device (3) together with a common control unit (6).