In a water treatment apparatus, microorganisms propagating on wood charcoal are activated by micro-nano bubbles contained in treatment water. Water treatment is carried out with the activated microorganisms propagated on the wood charcoal. Thereby, a stable treatment is achieved. Organic matters adsorbed by the wood charcoal are decomposed by the activated microorganisms propagated on the wood charcoal.

 
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> Scalable purification of AAV2, AAV4 or AAV5 using ion-exchange chromatography

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